Endocrine Abstracts

The aim of our study was to assess the advantage of combinative therapy with lisinopril and moxonidin for the treatment of arterial hypertension in group of obese patients in comparison to the single-drug therapy with lisinopril.Methods: 26 obese patients were divided in 2 groups. They underwent a 24-hour monitoring of the arterial pressure and were diagnosed as arterial hypertension II degree (ESH-ESC). In the I group for the purpose of stabiliza...

Background: The impact of hyperglycemia on atherogenesis is regulated through the increase of the oxidative stress, increase of the rest of the glycosylated products of metabolism and development of the endothelium dysfunction.Aim: To compare the biochemical indexes and investigate their relationship with the development of cardiovascular disease in obese patients with and without type 2 diabetes.Materials and methods: 21 patients ...

Background: The cardiovascular complication is the main cause of morbidity and mortality in obese patients. Endothelial dysfunction and atherosclerosis have the goal role in development of these diseases. The aim of our study was to reveal the role of nitric oxide during obesity associated arterial hypertension.Subject and method: 200 obese patients (age 35–55) were investigated. Control group comprised 25 healthy subjects. We calculated BMI, determ...